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The relationship of impulsivity to response inhibition and decision-making in remitted patients with bipolar disorder

Christodoulou, T and Lewis, M and Ploubidis, G B and Frangou, S (2006) The relationship of impulsivity to response inhibition and decision-making in remitted patients with bipolar disorder. European psychiatry : the journal of the Association of European Psychiatrists, 21 (4). pp. 270-3. ISSN 0924-9338. DOI UNSPECIFIED

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Abstract

BACKGROUND: Impulsivity, a core feature of bipolar disorder (BD), is a multifaceted concept encompassing failure of response inhibition and poor decision-making. Abnormalities in these two cognitive domains have been reported in BD patients but their relationship with impulsivity has not been explored. METHODS: Twenty-five remitted patients with BD completed the Barratt Impulsiveness Scale (BIS) and performed the Hayling Sentence Completion Task (HSCT) and a computerized version of the Iowa Gambling task. The HSCT total errors scaled score was used as a measure of response inhibition while the gabling task score, which reflects participants' ability to make advantageous choices, was used a measure of decision making. RESULTS: Higher scores on the BIS attentional and non-planning subscales were respectively associated with more errors in the HSCT and less advantageous choices in the gambling task. LIMITATIONS: All patients were medicated. Healthy participants were not included. CONCLUSIONS: Viewed in the context of recent relevant studies our findings suggest that impulsivity, response inhibition and decision-making in BD may represent behavioural manifestations of the same underlying biological mechanism possibly linked to ventral prefrontal cortical function.

Item Type: Article
Controlled Keywords: Attention, Bipolar Disorder, Cognition, Decision Making, Female, Gambling, Great Britain, Humans, Impulsive Behavior, Inhibition (Psychology), Male, Middle Aged, Psychiatric Status Rating Scales, Reaction Time, Self Disclosure, Task Performance and Analysis
Depositing User: Atira Pure
Date Deposited: 21 May 2014 15:54
Last Modified: 29 Jan 2015 09:10
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